New boss Frank Lampard brings his side to PO4 after succeeding Mark Robins at the end of November.
Pompey have fitness and form issues to contend with going into the game, at the start of five fixtures in 16 days.
Here’s how we think John Mousinho’s side will line up ahead of the clash.

9. RW Matt Ritchie
Looked jaded at Pride Park but will be charged up again for the start of the Christmas period. Photo: Jason Brown/ProSportsImages

10. Attacking midfield/No10: Callum Lang
Not he usual self last Friday, but who was in that Derby debacle. So much hinges on the Scouser's intensity. | National World

11. LW: Josh Murphy
Form has broadly been impressive of late with Murphy the one player with genuine pace to scare opposing defences. | National World

12. CF Colby Bishop
Thankless task for the Magic Man at Derby - the supply has to be better tomorrow. | The News
