The Blues may be condemned to a seventh successive season in League One, but there will still be 3,000-plus travelling fans making the trip to Pride Park.
It may be a meaningless game to Pompey but there’s everything riding on it for Paul Warne’s men, with three points a must for their play-off ambitions.
Here’s how we think John Mousinho will play it, as his side aim to give some reasons to be cheerful with the campaign nearing a close.
9. CM: Joe Morrell
Back with a point to prove, after four-game suspension. Photo: Jason Brown
10. RW: Paddy Lane
Really heartening to see the January arrival hit form late in the campaign, with coming off late last weekend nothing to be concerned about. Photo: Jason Brown
11. CF - Colby Bishop
The season may be over but the Magic Man will still have goals on his mind. Photo: Jason Brown
12. LW: Michael Jacobs
Unlikely to be here next season but likely needed now - and in decent form. Photo: Jason Brown