John Mousinho’s men go into the contest above Southampton after a solid start to the season has seen them pick up seven points from their opening four games.
The Blues go into the derby in a much stronger position than the previous meeting against the Saints in 2019, with the two rivals meeting in the Carabao Cup third round.
Pompey, who were under the leadership of Kenny Jackett, faced Ralph Hassenhuttl’s Premier League Southampton, who sealed a 4-0 triumph. A Danny Ings double and goals from Cedric Soares and Nathan Redmond secured the victory over the League One Blues.
But where is Jackett’s side from that last meeting?
We’ve taken a look at where Pompey’s starting and bench was from the most recent south-coast derby.
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5. CB: Oli Hawkins
Yes, that’s right. Pompey lined-up for their last south-coast derby with a striker playing at centre-back. Hawkins was utilised by Jackett in the heart of defence on a number of occasions during the 2019-20 campaign. The 33-year-old is back in his natural number nine role and has scored two goals in seven appearances in League Two for Barnet this season. | The News
6. LB: Brandon Haunstrup
The left-back was one of two academy graduates in the starting XI to face Southampton. However, injuries have since plagued the 28-year-old and is now appearing for Totton in the sixth tier of English football. | Habibur Rahman
7. CM: Tom Naylor
Naylor was in his second season at Fratton Park and was given the captain’s armband by Jackett at the start of the 2019-20 campaign. The midfielder has since been key to Chesterfield’s rise back to League Two and has featured 103 times for the Spireites in two seasons. | Getty Images
8. CM: Ben Close
Close was the third Fratton Park academy graduate named in the starting XI to face Southampton. Despite spending last season on loan with National League Eastleigh, the midfielder is back in Grant McCann’s plans at Doncaster and has featured five times this term. | PinPep Media / Joe Pepler