The Blues are aiming for successive victories after defeating Charlton Athletic 3-1 at The Valley on Tuesday evening.
And they’re looking to bounce back to success on their own patch following losses to Hull City and Lincoln last month.
Pompey’s automatic promotion push is being hampered by their form at PO4, having also lost to Wigan, Doncaster and Charlton this season.
What’s more, they face a Plymouth side who are unbeaten in their past five league games and recently beat Sunderland on their travels.
Kenny Jackett must weigh up which starting XI he believes will be best to defeat the Pilgrims.
The Blues boss made four changes at The Valley, although James Bolton replacing Jack Whatmough was enforced because of the latter’s suspension.
Scroll down and click through the pages to see how we think Pompey will line-up and who’ll be named among the substitutes.
5. Left-back - Charlie Daniels
It was somewhat of a surprise the January arrival replaced Lee Brown at Charlton but he delivered a fine performance both going forward and defending. Photo: Joe Pepler
6. Right-midfield - Ryan Williams
The Aussie was switched to the right flank at Charlton. He was perhaps quieter than he has been in recent games but still had big moments in the final third. Photo: Joe Pepler
7. Centre-midfield - Tom Naylor
The skipper bagged his seventh goal of the season at Charlton. In the form of his Pompey career. Photo: Graham Hunt
8. Centre-midfield - Andy Cannon
The fans' favourite is giving January recruits George Byers and Harvey White little chance to win his starting spot because of his excellent form. Bagged a deserved goal at Charlton. Photo: Daniel Chesterton