Who starts in goal is arguably the toughest shout the head coach has had make as boss, as he needs to decide between Gavin Bazunu and Alex Bass between the sticks.
Then there’s the formation. Does Cowley go with the midfield diamond again or switch back to a 4-2-3-1 formation?
There’s the debate over whether to continue with Arsenal’s Miguel Azeez, rest Louis Thompson and bring back the in-form Joe Morrell into the equation.
Don’t discount the significance of players returning to fitness against the Dons either.
We’ve used our nous and knowledge to come up with what we believe will be the way Cowley goes at Fratton Park tomorrow.
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9. Marcus Harness
Could return to the right if Cowley matches up Wimbledon's 4-2-3-1 formation, but in the form of his Pompey career and starts regardless. Photo: The News
10. Miguel Azeez
Could miss out if Cowley continues with a diamond or Hackett is deemed fit to start, but could also operate in the 10 position in a 4-2-3-1. Photo: The News
11. Ronan Curtis
Drive was so impressive against Wycombe. Certain to continue whether up front or off the left. Photo: The News
12. George Hirst
Confidence brimming after two excellent displays. More of the same please. Photo: The News