Who starts in goal is arguably the toughest shout the head coach has had make as boss, as he needs to decide between Gavin Bazunu and Alex Bass between the sticks.
Then there’s the formation. Does Cowley go with the midfield diamond again or switch back to a 4-2-3-1 formation?
There’s the debate over whether to continue with Arsenal’s Miguel Azeez, rest Louis Thompson and bring back the in-form Joe Morrell into the equation.
Don’t discount the significance of players returning to fitness against the Dons either.
We’ve used our nous and knowledge to come up with what we believe will be the way Cowley goes at Fratton Park tomorrow.
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17. Reeco Hackett
Back in training and likely to play some part, perhaps most likely off the bench Photo: The News
18. Ellis Harrison
Another back in training and getting closer to being available for selection. Photo: JPIMedia
19. Gassan Ahadme
Got on at Wycombe - and will be looking for more game time against the Dons. Photo: The News