Pompey will be looking to keep up their impressive home league record against their foes along the M27, who haven’t won in league action at PO4 for 50 years.
But how does John Mousinho aim to come out on top, amid his side’s injury crisis with 10 players sidelined?
Here’s how Pompey writer Jordan Cross think’s he’ll go in the high noon showdown at Fratton Park.
9. RW Adrian Segecic
Two goals in two for the little Aussie dynamo, with Pompey's top scorer coming to the boil nicely again. Photo: Graham Hunt
10. Conor Chaplin - 7
Always so positive on the ball and such a progressive player, which is a vital outlet for the Blues. Still nowhere near to scoring, though, and elected to pass rather than shoot with one second-half effort. Goal continues to elude. Photo: Graham Hunt
11. LW Millenic Alli
An impressive start to his Pompey career for the new loanee, who will be central to his side's chances of success - especially in the absence of Josh Murphy. | Portsmouth FC Photo: Portsmouth FC
12. CF Colby Bishop
Will have to go to the well again, as he leads the line in the absence of any senior support in the number nine position. Photo: Graham Hunt