And the big challenge for the Blues will be filling the huge void left by Alex Robertson’s season-ending hamstring injury.
Last week it was Gavin Whyte who got the nod to play in the 10 role in the 4-2-3-1 formation favoured by John Mousinsho this term.
Here’s how we think he will go as Leyton Orient arrive at PO4.
9. RW: Abu Kamara
Caught the eye once again at Cheltenham, with quality of running standing out once more. Photo: Jason Brown
10. ACM: Christian Saydee
The big question is how to Pompey fill an Alex Robertson-sized void? Gavin Whyte didn't do enough at Cheltenham with Terry Devlin another consideration. Suspicion is Mousinho may be more front-footed at home and go with Saydee. Photo: Jason Brown
11. LW Paddy Lane
Winger says he's in the form of his career - and we aren't about to argue with that. Photo: Jason Brown
12. CF Colby Bishop
Couple of chances went begging at Cheltenham - so we fully expect a goal at Fratton. Photo: Jason Brown