And the big challenge for the Blues will be filling the huge void left by Alex Robertson’s season-ending hamstring injury.
Last week it was Gavin Whyte who got the nod to play in the 10 role in the 4-2-3-1 formation favoured by John Mousinsho this term.
Here’s how we think he will go as Leyton Orient arrive at PO4.
5. CB Conor Shaughnessy
A costly gaffe last weekend hurt Pompey last weekend, but it's a rare blip in an otherwise outstanding season. Photo: Jason Brown
6. LB Jack Sparkes
Connor Ogilvie on the way back to step up competition for defender whose been among side's most impressive performers over past couple of months. Photo: Jason Brown
7. CM Joe Morrell
A bleak afternoon at former club Cheltenham last weekend, but Morrell was one of the players to emerge with credit at Whaddon Road. Photo: Jason Brown
8. CM Marlon Pack
Player of the month nomination says it all about current Pompey form. Photo: Jason Brown