The Blues have an injury doubt in Marlon Pack heading into the game, with the club captain nursing an ankle injury from Saturday’s win against Wigan.
Connor Ogilvie, Anthony Scully, Kusini Yengi and Tom Lowery also remain out, leaving John Mousinho with a bit of a selection headache.
But with the Blues in impressive form this season and having plenty of options within the squad to chose from, there’s no need to panic.
Here’s how we believe the Blues will line up tonight, despite the absence of some key players.
9. Right-wing: Paddy Lane
Three goals in three games, Pompey fans are starting to really see what the Northern Ireland international brings to the table. Is a shoo-in to start! Photo: Jason Brown
10. No10 role: Christian Saydee
Every cloud has a silver lining - and Pack's woes could be Saydee's gain tonight. The Fratton favourite got 30 minutes under his belt against Wigan on Saturday and quickly reminded fans what's he's all about. The Fratton faithful will love it if he's handed a recall as Alex Robertson drops back into the centre of the park. Photo: Jason Brown
11. Left-wing: Abu Kamara
You suspect John Mousinho might be tempted to unleash Gavin Whyte again after his impressive cameo at Wigan on Saturday. But with Kamara growing in influence and stature game by game, it would be harsh to drop him to the bench tonight. Photo: Jason Brown
12. Striker: Colby Bishop .
Never really got a chance at Wigan but his importance to the team remains immense. Photo: Jason Brown