The Blues may be condemned to a seventh successive season in League One, but there will still be 3,000-plus travelling fans making the trip to Pride Park.
It may be a meaningless game to Pompey but there’s everything riding on it for Paul Warne’s men, with three points a must for their play-off ambitions.
Here’s how we think John Mousinho will play it, as his side aim to give some reasons to be cheerful with the campaign nearing a close.
1. Pompey predicted line-up
Here's how we think Pompey will line up at Derby Photo: Jason Brown
2. GK Matt Macey
Not so much whether he will start, the question more becoming will the keeper be at Pompey permanently? Photo: Jason Brown
3. RB Joe Rafferty
Will be right in the conversation when it comes to Pompey's player of the season. Photo: Jason Brown
4. CB: Di'Shon Bernard
An argument to return to Sean Raggett's strength and experience, but would be harsh on the defender's who's been excellent in the past two games. Photo: Jason Brown