Pompey will be hoping for a change in fortune when they welcome Championship rivals Wrexham to Fratton Park tonight.
Both sides are sitting in the bottom half of the table ahead of their first league meeting since 1983 - but it is Blues who sit closest to the relegation zone in 20th-place, with John Mousinho’s men having just a four-point advantage on the bottom three.
For Wrexham, their motivation is clear as a win over Pompey would lift Phil Parkinson’s men into the top eight if results elsewhere fall in their favour.
Both Mousinho and Parkinson are already dealing with some key injury absentees that have hampered their attempts to build momentum this season - but what is the latest injury news from both sides as they prepare to face off on Wednesday night
Your next Portsmouth read: Update provided on 'absolute mountain' ahead of Portsmouth's game against Wrexham at Fratton Park
1. Lewis Brunt - Out
The Wrexham defender suffered a long-term thigh injury in a draw with Middlesbrough. | West Bromwich Albion FC via Gett
2. Nicolas Schmid - Out
Pompey continue to be without the number one after fracturing his hand during the south coast derby last month. The Austrian stopper was initially expected to be out for up to 12 weeks, but the issue didn't require surgery. | Pro Sports Images
3. Aaron James - Out
The Dragons defender is facing a lengthy spell on the sidelines after undergoing knee surgery. | Getty Images
4. Conor Shaughnessy - Out
Shaughnessy remains sidelined due to a hamstring issue and isn’t expected to return until December at the earliest. | Jeff Mood/ProSportsImages