The Pompey boss is calling the next three fixtures spread across eight days a potentially season-defining period for his side, as they face teams in and around them towards the foot of the table.
Charlton are also talking up the importance of the occasion, after four defeats on the spin as they slip down the Championship after their impressive return to the level.
There’s plenty to consider in terms of suspension, form and Pompey’s hunt for the right dynamic and winning formula. Here’s how Pompey writer, Jordan Cross, thinks Mousinho will go at The Valley.
9. RW Callum Lang
Now he's deemed fit to start, Lang has to be included. May still be finding his feet but remains absolutely central to Pompey getting their season going. | Paul Phelan/ProSportsImages
10. ACM John Swift
Could be the ideal stage to bring Swift back in after five games without a start. Some frustrating moments from Segecic in terms of his work-rate last weekend, with the Gosport lad offering more defensively with Segecic able to impact off the bench. | Graham Hunt/ProSportsImages
11. LW Josh Murphy
Levels have been pretty variable of late by Murphy's own high standards, with the key man needed to be at his best once again at the scene of his pre-season injury ahead of last term. | Ian Lyall/ProSportsImages
12. CF Colby Bishop
Everyone will be hoping things improve for Pompey's top scorer for the past three seasons. It needs to, with a goal needing to go in off his backside or similar to bury 15-game barren run impacting confidence. | Garahm Hunt