The Pompey boss is calling the next three fixtures spread across eight days a potentially season-defining period for his side, as they face teams in and around them towards the foot of the table.
Charlton are also talking up the importance of the occasion, after four defeats on the spin as they slip down the Championship after their impressive return to the level.
There’s plenty to consider in terms of suspension, form and Pompey’s hunt for the right dynamic and winning formula. Here’s how Pompey writer, Jordan Cross, thinks Mousinho will go at The Valley.
1. Pompey predicted line-up v Charlton Athletic
Here's how Pompey writer Jordan Cross thinks John Mousinho's side will line up at The Valley. | Graham Hunt/ProSportsImages
2. GK Nicolas Schmid
Assumed his role as a nailed-on starter since returning from hand fracture. | Paul Phelan/ProSportsImages
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3. RB Terry Devlin
Now this is an interesting one. Returns from one-game suspension after red card against Sheffield United. Jordan Williams put in reasonable enough display last weekend, but the Northern Ireland man was in good form before suspension. Don't discount the gritty competitor bolstering midfield, either. | Paul Phelan/ProSportsImages
4. CB Josh Knight
Needs a big game with his form variable and it potentially a physical clash at The Valley, with Knight likely up against Miles Leaburn at some stage. Photo: Graham Hunt