John Mousinho’s side face an in-form side at Stadium MK, with Mark Jackson overseeing an upturn in fortunes to drag his side away from the drop zone.
Pompey need to keep their impressive form under the new boss going, however, to up the pressure on the top six.
They have players coming back into the equation for the clash – here’s how we think they will line up.
13. SUB - Josh Oluwayemi
Illness kept the keeper out last weekend. Should return for this one, however. Photo: Jason Brown
14. SUB Ryley Towler
On the bench last weekend after his impressive start, but steady when called upon. Likely to he handed a similar role at Stadium MK. Photo: Jason Brown
15. SUB: Marlon Pack
A fully-fit Marlon Pack starts in Pompey best team, no doubt, but after his knee issue could be eased back in gently. Photo: Jason Brown
16. SUB - Tom Lowery
A number of ways Lowery could start - either as an eight or a 10 - but Mousinho may prefer to bulk up his midfield on the road, which would favour Thompson coming in. Photo: Jason Brown