Chiefly the Blues boss has to decide whether to go with John Marquis or George Hirst at Adams Park.
Hirst staked his claim with a man-of-the-match performance on Tuesday night as Marquis continues to struggle for form.
Elsewhere, there’s Arsenal’s Miguel Azeez pushing for a start with Cowley admitting he could be down to as few as 14 fit senior players.
Here’s how we believe the Pompey boss will line up as they face a tough test at the high-flying Chairboys.
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17. Reeco Hackett
Will tight call between the in-form attacker and Azeez for who starts behind the striker. Photo: The News
18. Gassan Ahadme
Had a good game on Tuesday but outshone by Hirst who appears ahead of the Moroccan in the pecking order as a result. Photo: The News
19. John Marquis
A blank against non-league Harrow with Hirst shining on Tuesday could tip the balance against the striker. Photo: The News