After impressive wins over Gillingham, Sunderland and Northampton, confidence is riding high in the Blues camp going into the game.
But the same can be said for the Addicks, having triumphed in their past four league games.
It proves to be an intriguing clash and Kenny Jackett will once again have to get his team and tactics spot on to pick up a success.
But will the Pompey boss make any changes to his starting XI? And will he shuffle his bench? We take a look at the likely match-day 18...

13. Sub 2 - Rasmus Nicolaisen
Must be getting frustrated due to his lack of minutes, but there's no reason to change defence at the moment. Photo: Nigel Keene

14. Sub 3 - Cam Pring
The Bristol City loanee remains second-choice left-back. Photo: Joe Pepler

15. Sub 4 - Bryn Morris
Had a cameo off the bench against Northampton but struggling to win back a starting spot. Photo: PinPeP

16. Sub 5 - Ben Close
The Southsea lad continues to push for a starting spot and remains someone well regarded by Kenny Jackett. Photo: Joe Pepler

