After impressive wins over Gillingham, Sunderland and Northampton, confidence is riding high in the Blues camp going into the game.
But the same can be said for the Addicks, having triumphed in their past four league games.
It proves to be an intriguing clash and Kenny Jackett will once again have to get his team and tactics spot on to pick up a success.
But will the Pompey boss make any changes to his starting XI? And will he shuffle his bench? We take a look at the likely match-day 18...

5. Left-back - Lee Brown
A series of solid displays has meant he's no longer the subject of substantial flak from sections of supporters. Photo: Joe Pepler

6. Right-midfield - Ryan Williams
Pompey have won all four games in the Aussie's four league starts. Proving to be a key player. Photo: Joe Pepler

7. Centre-midfield - Tom Naylor
Will continue to be Pompey's beating heart in the engine room. Photo: Joe Pepler

8. Centre-midfield - Andy Cannon
Proving undroppable at the moment, having helped himself to two assets against Northampton. Photo: Joe Pepler

