The Blues’ League One promotion push has suffered a blow in their past two games, losing to rivals Hull and Lincoln.
With Pompey harbouring ambitions of a top-two finish, Kenny Jackett must find a way of delivering a result at an Addicks side also hoping to go up automatically.
The boss will be forced to make one change from the Lincoln defeat, with Jack Whatmough suspended for three games after receiving a red card.
But there could be temptation from Jackett to play some of his January recruits from the outset.
George Byers and Charlie Daniels both came off the bench against the Imps and there is growing clamour from sections of supporters for the pair to be given a chance.
Meanwhile, some fans also want to see Jordy Hiwula be given a crack after being left out of the past two squads.
Scroll down below to see how we think Pompey will line-up at The Valley…
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17. Sub 6 - Ronan Curtis
May just need a rest after a tough shift against Lincoln while his threat going forward has taken a dip. Still an excellent option to have from the bench. Photo: Joe Pepler
18. Sub 7 - Ellis Harrison
The striker is likely to feature off the bench at some point after not making a league start for two months. Photo: Jason Brown