It's a tough assignment for John Mousinho's side against opposition with one of the best home records in the division.
The Blues are on a nine-game unbeaten run, however, as they aim to move a step closer to the Championship.
Here's how we think Pompey will line up, as they embark on the run-in with 10 games remaining.
1. How we think the Blues will line up at Blackpool
Pompey predicted line-up | Jason Brown/ProSportsImages
2. GK Will Norris
Sixteen clean sheets and counting for a standout Pompey performer this season. | GK Will Norris Photo: Jason Brown
3. RB Joe Rafferty
Man-of-the-match performance from Joe Rafferty last weekend, with Zak Swanson back to step up competition. | Jason Brown/ProSportsImages
4. CB Sean Raggett
Battled back from penalty setback last weekend to put in another powerful performance. Photo: Jason Brown
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