The Blues may be the league’s form side but it's a tough assignment as they take on the Tractor Boys, who are also in good form themselves under new boss Kieran McKenna.
McKenna’s men are unbeaten in eight and were touted as the division’s best side by Lincoln boss Michael Appleton, after his side were defeated 2-0 on Tuesday night.
Danny Cowley has to consider how best to contain the big spenders, who could afford to name the likes of Conor Chaplin, James Norwood, Joe Pigott and Macauley Bonne on the bench at Portman Road last time out.
There are Pompey selection considerations all over the pitch, including who starts at left wing-back and in the middle of midfield, but particularly who partners George Hirst up front.
Here’s how we think Cowley will go in Suffolk.
A message from the Editor, Mark Waldron
You can support our local team of expert Pompey writers by subscribing here for all the latest news from Fratton Park for less than 25p per week.
5. LCB: Clark Robertson
Could be a consideration to put Ogilvie in the middle and start Hume at wing-back, depending whether Cowley wants strength or greater mobility in his side. Photo: The News
6. RWB: Mahlon Romeo
So dependable and a nailed-on starter on the right flank. Photo: The News
7. CM: Louis Thompson
Taken off with 20 to go at Crewe, which suggests the key midfielder was being saved for this clash. Photo: The News
8. CM: Joe Morrell
Tenacious at Crewe and performing to the level we've come to expect of Welshman. Photo: The News