Pompey will be looking to keep up their impressive home league record against their foes along the M27, who haven’t won in league action at PO4 for 50 years.
But how does John Mousinho aim to come out on top, amid his side’s injury crisis with 10 players sidelined?
Here’s how Pompey writer Jordan Cross think’s he’ll go in the high noon showdown at Fratton Park.
17. Sub 5 Luke Le Roux
Interesting how it pans out for the South African man this month, with Zak Swanson being favoured in midfield at Sheffield Wednesday a damning statement. Photo: Graham Hunt
18. Sub 6: Marlon Pack
Skipper's expected to be back from injury and will be desperate to play a part in the game. | Graham Hunt
19. Sub 7 John Swift
Other options being favoured in the central areas of the pitch at present. Photo: Graham Hunt
20. Sub 8 Keshi Anderson
Didn't get over the line in time to feature on Wednesday, so a great occasion for new boy to potentially make his debut. | Portsmouth FC