John Mousinho’s side are out to make it 27 league games unbeaten against the Tangerines and retain their spot at the head of League One.
The Blues have injury issues to deal with as many as six first-teamers sidelined. Here’s how we think Mousinho will go.
13. Sub 1: Ryan Schofield
Remains the understudy - but performed well last time at Orient. Photo: Jason Brown
14. Sub 2: Ryley Towler
Not far from the starting XI after impressing with the armband at Leyton Orient in the Trophy recently. Photo: Jason Brown
15. Sub 3: Zak Swanson
Has to be in arguably the tightest battle for playing time in the Pompey squad. If not against Blackpool, there will be playing time on the horizon. Photo: Jason Brown
16. Sub 4: Terry Devlin
Started the past two league games and in the Cup at Chesterfield. That shows he's firmly in Mousinho's thinking and could well continue, but perhaps a berth on the bench after a busy period is the right call for Northern Ireland lad. Photo: Jason Brown