Positive developments on the injury front – apart from Joe Rafferty’s groin problem – also gives the Blues boss the chance to welcome back some of his previous walking wounded.
But will he dare to rush the likes of Marlon Pack and Tom Lowery back when there’s an important league trip to Morecambe just around the corner?
Currently, only four of Pompey’s five loan players have been granted permission to feature in the Cup for the club this season.
That will also need to be taken into consideration.
So, with all that in mind, what can we expected the Blues’ starting XI to look like tonight?
Here’s how we think they’ll line up at Edgar Street…
9. Ronan Curtis - left-wing
Tonight's game could prove to be a scrappy one as Hereford look for a Cup upset. Pompey will need to be up for it, so who better to call upon in such circumstances, especially when the forwards will need to do their fair share of defending. Attacking threat will be important as well. Photo: Jason Brown
10. Colby Bishop - Centre-forward 1
Given the striker's non-league background, this fixture will be right up the former Leamington man's street. Pompey will also need his goals given Dane Scarlett and Joe Pigott's recent struggles. Photo: Barry Zee
11. Dane Scarlett - centre-forward 2
The young Spurs striker hasn't scored in nine games for the Blues. Could see tonight as the ideal opportunity to rectify that. Photo: Jason Brown