The Blues are dealing with extensive injury issues, with 10 players sidelined for the game.
John Mousinho is bolstered by some new faces for the game, however, with seven additions landed across the winter transfer window.
Here’s how Pompey writer, Jordan Cross, thinks Mousinho will go at Deepdale.
1. Pompey predicted line-up
Here's how Pompey writer Jordan Cross thinks the Blues will line up at Deepdale. | The News
2. GK: Nicolas Schmid
Likely to be busier at Deepdale, after a relatively straightforward clean sheet against West Brom. | Graham Hunt/ProSportsImages
3. RB: Terry Devlin
Still a Pompey player after Wrexham's interest - a deal which may have caused a riot if it'd been agreed! | Graham Hunt/ProSportsImages
4. CB: Regan Poole
What a warrior. Dismissed injury worries to player the full match against West Brom. Such a key figure, especially at present. | Graham Hunt/ProSportsImages