Terry Devlin’s suspension for his red card handball at Sheffield United guarantees at least one change, as the Northern Ireland man serves a one-game suspension.
There are many other players whose continuing involvement will be under the microscope, after the weak 3-0 loss at Bramall Lane.
Here’s how Pompey writer Jordan Cross think John Mousinho will go, as his side look to avoid falling into the Championship relegation places.
13. Sub 1: Josef Bursik
Back-up spot remains Bursik's ahead of Ben Killip and Jordan Archer. Photo: Graham Hunt
14. Sub 2 Hayden Matthews
Has been favoured over Ibane Bowat as first central defensive back-up. Photo: Graham Hunt
15. Sub 3 Luke Le Roux
One definite change in the squad with Terry Devlin suspended. We've gone for the South African to come in on the bench. Photo: Simon Roe
16. Sub 4 Marlon Pack
Not started for four games, but could well be the occasion for the skipper to add his calm quality. Close call between Pack, John Swift and Mark Kosznovszky. Photo: Graham Hunt