John Mousinho’s men have picked up 10 points from a possible 12 and go into the game two points off the play-offs.
Meanwhile, Burnley have hugely struggled since their Premier League relegation, this week setting a new English record for the longest period without a home league win.
The Clarets will be looking for a new manager bounce, however, after the appointment of Fabio Celestini this week.
Both teams have injuries going into the game, though Pompey are set to welcome Josh Murphy and Conor Shaughnessy back into the fray.
Here’s how Blues writer Jordan Cross thinks Mousinho will go.
9. RW Abu Kamara
Mousinho's faith in the winger is unwavering, but will be hungry to get off the mark with a goal after Fratton homecoming. | Jason Brown
10. CAM Adrian Segecic
Looking to add to his five goal involvements so far. A case to utilise Ebou Adams as a 10, though we've gone for Segecic to continue. | Jason Brown
11. LW Ryan Kavuma-McQueen
Another close one with Shade the other contender to start. Kavuma-McQueen looked tired against Millwall last week, so would've benefitted from the clear week. | Jason Brown
12. ST: Marko Milovanovic
Three goals for Marezi so far, but now played five games without a finish from open play - a stat he'll be looking to put right this weekend. | Jason Brown