Following Wednesday’s 2-2 draw at PO4 against Watford, the Blues have a quick turnaround as they welcome Middlesbrough.
John Mousinho’s men have had a tough start to the campaign, winning just two of their opening eight games, which has seen them pick up nine points and currently sit 17th in the standings.
Meanwhile, Boro have shot out of the blocks quickly under new boss Rob Edwards and are one of two sides yet to taste defeat in the league so far.
Middlesbrough have picked up five points from their last three games, which also included another long trip to the south coast to face Southampton.
We’ve taken a look at the early team and injury news from both camps ahead of this afternoon’s contest at Fratton.
Your next Pompey read: Portsmouth v Middlesbrough: Jordan Cross' predicted line-up as leaders arrive at Fratton
5. Dael Fry - Doubt
Fry has been working his way back from a calf injury but is expected to be fully fit for the long trip to the south coast. | Getty Images
6. Callum Lang - Out
Lang’s recovery is going well according to Mousinho, who has pencilled in a return date of November for the popular forward. The head coach has earmarked the Blues’ Fratton fixture against Millwall as his potential comeback. | Alun Roberts/ProSportsImages
.jpeg?crop=4:3&trim=&width=800)
7. Seny Dieng - Out
The goalkeeper is yet to return from an ACL injury sustained in December, which saw him undergo surgery a month later. | Getty Images
.jpeg?crop=4:3&trim=&width=800)
8. Josh Murphy - Doubt
Murphy continues to be a huge doubt, having missed the previous three games with an ankle injury. Mousinho has again reiterated the forward is 50/50 for this afternoon’s contest but is yet to return to full training. Gave the Fratton faithful a huge boost heading into the contest, having penned a new long-term deal on Thursday. | Graham Hunt/ProSportsImages