There is no time to waste for Pompey, who are straight back in action today after Saturday evening's trip to Leicester City.
A tough challenge awaits for the Blues tonight, though, with early pace setters Coventry City making the journey to the south coast.
Frank Lampard’s men currently top the standings and are the only side who remain undefeated in the Championship after the opening 10 games.
Ahead of this evening’s contest, we’ve taken a look at the early team and injury from both camps. Here’s the latest.
5. Nicolas Schmid - Out
Although Josef Bursik has stepped up to the plate in recent weeks, Pompey are still without their number one, who remains sidelined with injury. The stopper fractured his hand during the south coast derby last month. | Getty Images
6. Josh Murphy - Out
Mousinho delivered some positive news on the injury front over the winger, who has missed the Blues’ previous five matches with an ankle. Although Murphy won’t be fit to feature this evening, he did return to training on Monday with the hope of playing against Stoke City on Saturday. | Graham Hunt/ProSportsImages
7. Josh Eccles - Out
Lampard is set to welcome Eccles back into the squad this evening after missing the Sky Blues’ previous two Championship contests with a gluteal injury. | Getty Images
8. Conor Shaughnessy - Out
Shaughnessy is expected to be out for a significant period after sustaining a hamstring issue against Sheffield Wednesday last month. The centre-back could be back involved in December after being given a 12-week timeframe before a possible return. | Stephen Flynn/ProSportsImages