John Mousinho’s men are desperately trying to arrest a run of five games without a win, as they go to Loftus Road.
There’s big calls for the Pompey boss to make, as he looks to repeat successes on the road in the capital against Millwall and Charlton last month.
Here’s how Pompey writer Jordan Cross thinks the Blues head coach will go.
17. Sub 5: Luke Le Roux
Midfield back-up role with Andre Dozzell still sidelined. | Stephen Flynn/ProSportsImages
18. Sub 6: Adrian Segecic
Could well be a scenario where Segecic starts on the right flank or as a 10. Definitely will play some part in the game. | Graham Hunt/ProSportsImages
19. Sub 7: Conor Chaplin
Still searching for his most effective form. | Simon Roe/ProSportsImages
20. Sub 8: Jacob Brown
Offered something different up front against Derby, but probably not effective enough to definitely keep his place in the team. Photo: Justin Setterfield