The Blues head north to Gresty Road, after a powerful second-half showing in the 4-0 success against Doncaster Rovers last weekend.
Cowley named what he felt was the most attacking team of his Pompey reign against Gary McSheffrey’s men.
Now he has to decide whether to go with the same again, as they face another struggling team in the Railwaymen.
A start for Aiden O’Brien is also a big consideration after his goal off the bench at Fratton Park, while high-profile January arrival Tyler Walker has yet to score in five starts.
We’ve pulled together what we know to deliver what we feel will be Pompey’s line-up for the game.
A message from the Editor, Mark Waldron
You can support our local team of expert Pompey writers by subscribing here for all the latest news from Fratton Park for less than 25p per week.
Now he has to decide whether to go with the same again, as they face another struggling team in the Railwaymen.
![Has been central to Pompey's best attacking play of late. Would be a massive call from Cowley to take him out.](https://www.edinburghnews.scotsman.com/webimg/b25lY21zOjY5MTU2Y2EwLTZhNDctNDMyNy1iNDFkLWRjY2E4YWNlZGUxNDo1NWQ5ZDA4ZC1jYmI3LTRiY2UtYTY3Ny02NGVjNTQ5MTY5N2Q=.jpg?crop=3:2&trim=&width=640)
9. CM: Michael Jacobs
Has been central to Pompey's best attacking play of late. Would be a massive call from Cowley to take him out.Photo: The News
![A goal and plenty of industry against Doncaster means the striker deserves to keep his place.](https://www.edinburghnews.scotsman.com/webimg/b25lY21zOmVjMzE3MmM1LTEzMzAtNGIyOS1hMTU4LTI5NmQwODBlZGJhZTo1OWJlNzRhYi1iNTc3LTQ5MGMtODk2ZS1jNDY1MmUxZTk3NDQ=.jpg?crop=3:2&trim=&width=640)
10. ST: George Hirst
A goal and plenty of industry against Doncaster means the striker deserves to keep his place.Photo: The News
![Big debate about whether the high-profile signing continues after five games without a goal or Aiden O'Brien comes in. Close call but Cowley has faith in the Coventry man.](https://www.edinburghnews.scotsman.com/webimg/b25lY21zOjJiZDdiNDY2LTVhNWUtNGZlZS04NzQ4LWJjZjE4MDJhYzNmNjo3MzMzNzExOC1kYzNhLTRiMGItODNjYy05OTYyZGM4NzBkMGY=.jpg?crop=3:2&trim=&width=640)
11. ST: Tyler Walker
Big debate about whether the high-profile signing continues after five games without a goal or Aiden O'Brien comes in. Close call but Cowley has faith in the Coventry man.Photo: JPIMedia
![Set to continue as back-up to Bazunu at Gresty Road.](https://www.edinburghnews.scotsman.com/webimg/b25lY21zOmE2ZjdlYzg3LTQ3MzYtNGFkZC04NDUwLWEyNzdlYmVkNTFkMTphMjRlMTY2Yy1kZDYxLTQyZDEtODA5Zi01MDhkM2YwMGMyMTQ=.jpg?crop=3:2&trim=&width=640)
12. Sub 1: Ollie Webber
Set to continue as back-up to Bazunu at Gresty Road.Photo: Portsmouth FC