Danny Cowley’s side are out to make it seven wins on the spin against the League Two outfit at Fratton Park.
But how will the Blues boss go as he looks to keep the wins going against Simon Weaver’s men?
We’ve done our digging and come up with what we believe is the like Pompey line-up.
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17. Reeco Hackett
Played while injured last weekend. Brown is back and the pair could share the load at left wing-back. Photo: The News
18. Michael Jacobs
Both Cowley and Jacobs have admitted he has no natural place in the 3-4-1-2 formation. Photo: The News
19. Harry Jewitt-White
Arguably the most exciting of the current crop of youngsters could benefit from nine subs being used in the FA Cup. Photo: The News
20. Ellis Harrison
Pushing for a start with Hirst knowing he has to keep his fine form going. Photo: JPIMedia