It’s the Blues first trip to the CBS Arena since October 2018, when Ronan Curtis first-half strike continued Kenny Jackett’s men's impressive start to the 2018-19 League One season.
Now in the Championship, John Mousinho’s side will be looking to return to winning ways after Saturday’s 2-1 loss to Millwall.
The disappointment at The Den represented Pompey’s 14th away defeat of the campaign as they continue to struggle on their travels.
Nonetheless, that hasn’t deterred 2,300 members of the Fratton faithful from making the 280-mile round trip to the West Midlands.
The Sky Blues will be without boss Frank Lampard after he was given a one-game touchline ban following a red card against Burnley on Saturday.
With an exciting prospect ahead which could have repercussions at either end of the table, here’s the latest team news from both camps.
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13. Zak Swanson - Out
The right-back was a surprise absentee for Saturday’s game against Millwall, having started the 1-0 win against Blackburn a week prior. Mousinho confirmed Swanson had picked up a new heel injury, but isn’t expected to miss a long period. | National World
14. Ibane Bowatt - Out
The transfer deadline day arrival from Fulham is out for the rest of the season after picking up a knee injury in training back in September. | Portsmouth FC