At 2-0 after 79 minutes, the Blues looked out of it until substitute Reeco Hackett pulled one back and threatened to inspire a remarkable late comfortable.
However, in stoppage time, Plymouth hit the visitors on the break to seal their victory and a return to the top of the table, yet there were some positive Pompey performances.
Here are our on-the-whistle player ratings...
13. Michael Jacobs - 5
(Replaced by Dane Scarlett on 62 minutes). Couldn’t get involved in the match, with hosts dominating for long spells during his time on the pitch. There was a first-half header from Dale’s right-wing cross but a difficult chance which flew well over. Photo: National World
14. Connor Ogilvie (6) of Portsmouth on the attack during the EFL Sky Bet League 1 match between Plymouth Argyle and Portsmouth at Home Park, Plymouth, England on 11 February 2023.
Connor Ogilvie takes on Joe Edwards during Pompey's clash with promotion hopefuls Plymouth. Picture: Graham Hunt/ProSportsImages Photo: Graham Hunt
15. Dane Scarlett - 6
(Replaced Michael Jacobs on 62 minutes) Helped pep Blues but should have put Lane through on goal after a sensational run from own half. Photo: National World
16. Paddy Lane - 6
(Replaced Owen Dale on 68 minutes) His corner from the left helped create Reeco Hackett's consolation which threatened a potential comeback. Lively once more and undoubtedly pushing for a start. Photo: xxxxx